Gallbladder (GB) stones (~Pittashaya ashmari) are formed within the lumen of the GB and cause obstruction in the smooth flow of bile during physiological contraction of the bladder. The research backup for this study is based on the available knowledge of Ayurveda regarding the management of GB stones. Ayurveda may have the potential to offer practical inputs to this burgeoning area. An attempt has been made here to take a view of certain characteristic aspects of Ayurveda approaches with particular reference to their compatibility with modern needs. A patient diagnosed with Pittashaya ashmari (~calculus cholecystitis) has been treated with Ayurveda modalities. The clinical presentations of this case have been assessed based on classical signs and symptoms of Ashmari (~lithiasis) mentioned in Ayurveda classics. In modern medical science, no medicinal cure has been found yet to treat this disease. Only excision of the GB or destruction of the stones by lithotripsy through microsurgery is suggested. However, in Ayurveda, different medicines administered orally with some specific Anupana (~adjuvant) are effective. A case is being presented, which was treated as per the treatment principles of Samshodhana (~cleansing therapy) as Koshthashuddhi (~mild purgation) and Sukha-virechana (~purgation) with Pittashmaribhedana prabhava (~stone crushing effect) of some specific Ayurveda medications. Follow-up has been taken two times after treatment by assessing improvement in the classical sign and symptoms of Ashmari (~lithiasis) and ultrasonography report as well. A significant clinical and radiological improvement was noted in this case.

Allergic responses are found a major reason for occupational contact dermatitis and have a prevalence of 30% of reported cases. Those exposed to pesticide spraying have been more prevalent of being affected with occupational contact dermatitis. A 46-year-old female, working in agriculture fields, presented to the hospital with chief complaints of intense fissuring, painful cuts, scaly, and itchy lesions affected over the palms of both hands and sides of fingers for the four months. She frequently come across the pesticides while mixing them, spraying on crops, sowing pesticide-preserved seeds, and harvesting previously treated crops that recurred every season mainly during the rainy season. The present case of palmar dermatitis was treated with the principles of Gara visha chikitsa. The major symptoms such as Kandu (~itching), Twak paka (~inflammation), Vedana (~pain), Sphutana (~cracking of skin), and Rukshata (~roughness) were reduced within 20 days of treatment; major lesions healed within one month of treatment. After 90 days, lesions were completely healed, and no fresh symptoms were noticed even during the follow-up period of one month. The present observation and approach endorse a step toward the practice of Ayurvedic intervention in pesticide-induced hand dermatitis.

Transient lingual papilitis is a common inflammatory hyperplasia of one or multiple fungiform lingual papillae that has acute onset. It is painful and transient. Based on the clinical features, the condition can be compared with Pittaja jihvakantaka. In the present case report, a 35-year-old male patient presented with a chief complaint of nodular growth on the dorsal surface of his tongue for 4 months. The growth persisted even after intake of systemic steroids and even after avoiding possible mechanical stimuli. Considering the pathology and symptomatology, Triphala guggulu, Kamadudha rasa, Sutashekhara rasa, Ajamodadi churna, and Haridra khanda were prescribed. Anu taila and Yashtyadi taila were given for Pratimarsha nasya (~low-dose medication through nasal route). After about four months of treatment, the associated symptoms subsided to a significant level. No adverse events were noted during the treatment and follow-up period of about three months. This case report sets an example that Ayurveda has an effective and safe treatment for conditions such as lingual papilitis. This case also becomes evidence and base for further research works with a larger sample size.

The incidental diagnosis of neoplasms has greatly increased due to the widespread use of advanced imaging techniques. Pancreatic neuroendocrinal tumors (pNET) comprise 7% of the neuroendocrine tumors (NETs) that can be functional or nonfunctional. Nonfunctional pNETs are more common, which may further extend to the liver and produce symptoms such as loss of appetite, weight loss, and abdominal pain. A 47-year-old male, presented with loss of appetite, anorexia, weakness, and weight loss for the past three months. The patient was diagnosed with pNET and underwent precut sphincterotomy, common bile duct stenting, and Whipple surgery. Recurrent fever with previous complaints persisted even after surgery. The patient was advised to go for further operative procedures but he denied and decided to take Ayurveda treatment. Punarnavashtaka kwatha, Syrup Livomyn, Rohitakarishta, Avipattikara churna, Kutaki churna, and polyherbal decoction prepared with Bhumyamalaki (Phyllanthus niruri Linn.), Patolapatra (Trichosanthes dioica Roxb.), Guduchi (Tinospora cordifolia [Willd.] Miers.), Punarnava (Boerhavia diffusa Linn.), Rakta chandana (Pterocarpus santalinus Linn.), Parpataka (Fumaria parviflora Lam.), and Kiratatikta (Swertia chirata Buch.-Ham. ex Wall.) were prescribed after a thorough examination of the patient. After five months of treatment, the patient got relief from weakness, anorexia, and recurrent fever. Liver functions showed a significant improvement after the treatment. The patient had gained a body weight of four kg and he is able to do his day-to-day activities without lethargy.

Huntington's disease (HD) is a rare autosomal dominant neurodegenerative disorder. It is caused due to trinucleotide cytosine-adenine-guanine (CAG) repeat expansion on chromosome 4. The greater the CAG repeat size, the earlier the onset of the disease. It is characterized by motor, cognitive, and psychiatric symptoms. The onset of Juvenile HD occurs before the age of 21 and is rarer compared to adult-onset HD. A 30-year-old female, diagnosed with HD by molecular genetic analysis and magnetic resonance imaging, presented to Ayurveda hospital with chief complaints of abnormal involuntary movements in both the limbs bilaterally, difficulty in walking without support, difficulty in speech, swallowing, episodes of anger outbursts, and hard stools. The Ayurvedic treatment protocol was planned with a course of Nasya (~medication through nasal route), Basti (~medicated enema), and Abhyanga (~therapeutic oleation). Shashtika Shali Pinda Sweda (~sudation by application of poultice with rice), Shiropichu (~therapeutic procedure of placing tampon with oil over head region), and Karnapurana (~filling of ear with medicated liquid) along with internal medications which had Balya (~strength promoting), Brimhana (~restorative measures), Agni balavardhana (~enhancing digestive fire), Rechana (~cleansing), Rasayana (~rejuvenation therapy), and Vatahara (~Vata pacifying) actions were also adopted. By the completion of treatment, improvement was noticed in terms of reduced involuntary movements, better balance while standing, and reduced frequency of falls. Assessment by Abnormal Involuntary Movements Scale showed a reduction from score 30 to 18 after treatment, inferring that Ayurvedic therapies can help in betterment of patients affected with HD.

The smack addiction is very much spreading nowadays among the youth, which is injurious for a healthy society. Opiates are highly addictive. Long-term use of opiates causes dependence, leading to tolerance. Overdose incidents occur due to chronic intake or addiction that can lead to life-threatening complications. In the present case, a 21-year-old male with a history of smack addiction for the last three years presented to the outpatient department with withdrawal symptoms including tremors, running nose, watering eyes, body ache, sleeplessness, sweating, nausea, irritability, and diarrhea. The assessment of withdrawal symptoms was based on Clinical Opiate Withdrawal Scale (COWS). The multimodal treatment including Shirodhara (~oil dripping on the forehead) with Ashwagandha taila and Tila taila, Sarvanga abhyanga (~synchronized whole body massage with medicated oil) with Dashmoola taila, Svedana (~sudation) using Dashmoola kwatha, and Nasya (~medications through nasal route) with Jatamansi taila along with internal medications of Vishatinduka vati and Sameeragaja kesari rasa showed promising results. Within one month of the treatment, the withdrawal symptoms of smack addiction were reduced considerably. The COWS score decreased to 3 from 22 after three weeks of treatment, inferring that multimodal Ayurvedic treatment can be an effective and safe solution in case of smack addictions.

Hirayama disease (HD), also known as monomelic amyotrophy, is rare cervical myelopathy due to spinal cord compression by forward displacement of the posterior dural sac during neck flexion that manifests itself as asymmetrical, slowly progressive atrophic weakness of the forearms and hands predominantly in young males. A 23-year-old man came to the outpatient department with a complaint of weakness of the right upper limb for the past 3 years which started in the right hand and forearm along with tremors in both hands. Considering the clinical history, physical examination, and electromyography, the condition was diagnosed as HD by an allopathic consultant two years ago. The symptoms can be included under Vata vyadhi. Some of the symptoms such as Asthibheda (~splitting type of pain in the bones), Sandhishoola (~pain in joints), Mamsa kshaya (~diminution of muscle mass), and Bala kshaya (~diminished strength) come under Asthimajjagata vata. Following the symptomatology and its resemblance with Asthimajjagata vata, the patient was treated with Snehapana (~internal oleation) with Ashwagandha ghrita followed by Virechana karma (~purgation therapy). Anuvasana basti with Panchatikta kshira along with Shalishastika pinda svedana was done after Virechana. Rasayana kalpa ksheera chikitsa was given after completion of Basti procedure. After 40 days of treatment, the patient showed significant improvement in muscle bulk. The magnetic resonance imaging shows no neural compression. This case shows that Ayurveda treatment may be helpful in pathologies like HD. Further, better results may be obtained if Ayurvedic therapies start at an earlier stage and continued for a longer duration.